Atpenin A5, ubiquinone-binding site mitochondrial complex II inhibitor (ab144194)
Key features and details
- Highly selective, potent ubiquinone-binding site mitochondrial complex II inhibitor
- CAS Number: 119509-24-9
- Purity: > 95%
- Soluble in ethanol and in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Atpenin A5, ubiquinone-binding site mitochondrial complex II inhibitor -
Description
Highly selective, potent ubiquinone-binding site mitochondrial complex II inhibitor -
Purity
> 95% -
CAS Number
119509-24-9 -
Chemical structure
Properties
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Chemical name
3-[(2S,4S,5R)-5,6-Dichloro-2,4-dimethylhexanoyl]-4-hydroxy-5,6-dimethoxy-1H-pyridin-2-one -
Molecular weight
366.24 -
Molecular formula
C15H21Cl2NO5 -
PubChem identifier
54676868 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol and in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C[C@@H](C[C@H](C)C(=O)C1=C(C(=C(NC1=O)OC)OC)O)[C@H](CCl)Cl -
Source
Synthetic
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Research areas
Images
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Chemical Structure - Atpenin A5, ubiquinone-binding site mitochondrial complex II inhibitor (ab144194)2D chemical structure image of ab144194, Atpenin A5, ubiquinone-binding site mitochondrial complex II inhibitor
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab144194 has been referenced in 1 publication.
- Yancey DM et al. Cardiomyocyte mitochondrial oxidative stress and cytoskeletal breakdown in the heart with a primary volume overload. Am J Physiol Heart Circ Physiol 308:H651-63 (2015). IHC-P ; Rat . PubMed: 25599572