BAM (8-22) (Bovine Adrenal Medulla 8-22), SNSR agonist (ab120178)
Key features and details
- SNSR agonist
- CAS Number: 412961-36-5
- Soluble in water
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
BAM (8-22) (Bovine Adrenal Medulla 8-22), SNSR agonist -
Description
SNSR agonist -
Alternative names
- Bovine Adrenal Medulla 8-22
- GPCR
- MAS related gene MRGX1
see all -
Biological description
Endogenous peptide fragment that is a selective agonist for the sensory neuron specific receptor (EC50 values are 28 and 14 nM for SNSR3 and SNSR4, respectively). Inhibits development of morphine tolerance in rats, and exerts spinal analgesic effects by an interaction with NMDA receptors.
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CAS Number
412961-36-5 -
Chemical structure
Properties
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Molecular weight
1971.22 -
Molecular formula
C91H127N25O23S -
Sequence
VGRPEWWMDYQKRYG -
PubChem identifier
16158367 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas
Images
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Chemical Structure - BAM (8-22) (Bovine Adrenal Medulla 8-22), SNSR agonist (ab120178)2D chemical structure image of ab120178, BAM (8-22) (Bovine Adrenal Medulla 8-22), SNSR agonist
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (1)
ab120178 has been referenced in 1 publication.
- Liu YJ et al. Involvement of MrgprC in Electroacupuncture Analgesia for Attenuating CFA-Induced Thermal Hyperalgesia by Suppressing the TRPV1 Pathway. Evid Based Complement Alternat Med 2018:9102107 (2018). PubMed: 29619074