Key features and details
- Potent antiangiogenic agent. Selective threonyl-tRNA synthetase inhibitor.
- CAS Number: 7184-60-3
- Purity: > 98%
- Form / State: Solid
- Source: Streptomyces sp.
Product nameBorrelidin, threonyl-tRNA synthetase inhibitor
DescriptionPotent antiangiogenic agent. Selective threonyl-tRNA synthetase inhibitor.
Chemical name(1R,2R)-2-[(2S,4E,6Z,8R,9S,11R,13S,15S,16S)-7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6-dien-2-yl]cyclopentane-1-carboxylic acid
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab144212 has been referenced in 1 publication.
- Jeong SJ et al. Inhibition of MUC1 biosynthesis via threonyl-tRNA synthetase suppresses pancreatic cancer cell migration. Exp Mol Med 50:e424 (2018). PubMed: 29328069