Borrelidin, threonyl-tRNA synthetase inhibitor (ab144212)
Key features and details
- Potent antiangiogenic agent. Selective threonyl-tRNA synthetase inhibitor.
- CAS Number: 7184-60-3
- Purity: > 98%
- Form / State: Solid
- Source: Streptomyces sp.
Overview
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Product name
Borrelidin, threonyl-tRNA synthetase inhibitor -
Description
Potent antiangiogenic agent. Selective threonyl-tRNA synthetase inhibitor. -
Purity
> 98% -
CAS Number
7184-60-3 -
Chemical structure
Properties
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Chemical name
(1R,2R)-2-[(2S,4E,6Z,8R,9S,11R,13S,15S,16S)-7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6-dien-2-yl]cyclopentane-1-carboxylic acid -
Molecular weight
489.64 -
Molecular formula
C28H43NO6 -
PubChem identifier
6436801 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C[C@H]1C[C@H](C[C@@H]([C@H](/C(=C\C=C\C[C@H](OC(=O)C[C@@H]([C@H](C1)C)O)[C@@H]2CCC[C@H]2C(=O)O)/C#N)O)C)C -
Source
Streptomyces sp.
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Research areas
Images
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Chemical Structure - Borrelidin, threonyl-tRNA synthetase inhibitor (ab144212)2D chemical structure image of ab144212, Borrelidin, threonyl-tRNA synthetase inhibitor
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab144212 has been referenced in 1 publication.
- Jeong SJ et al. Inhibition of MUC1 biosynthesis via threonyl-tRNA synthetase suppresses pancreatic cancer cell migration. Exp Mol Med 50:e424 (2018). PubMed: 29328069