Key features and details
- Selective α2A adrenoceptor antagonist
- CAS Number: 681806-46-2
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameBRL 44408 maleate, alpha2A adrenoceptor antagonist
DescriptionSelective α2A adrenoceptor antagonist
Selective α2A adrenoceptor antagonist (Ki values are 5.68 and 651 nM for α2A and α2B, respectively). Centrally active following subcutaneous administration. Demonstrates antidepressant and analgesic activity.
Chemical name2-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-2,3-dihydro-1-methyl-1H-isoindole maleate
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120806 has been referenced in 1 publication.
- Li Q et al. Sympathetic Denervation Ameliorates Renal Fibrosis via Inhibition of Cellular Senescence. Front Immunol 12:823935 (2021). PubMed: 35140713