Cisplatin, antineoplastic agent (ab141398)
Key features and details
- Potent, broad spectrum antineoplastic agent
- CAS Number: 15663-27-1
- Soluble in water to 5 mM (with sonication) and in 0.9% w/w NaCl to 5 mM (with sonication)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Cisplatin, antineoplastic agent -
Description
Potent, broad spectrum antineoplastic agent -
CAS Number
15663-27-1 -
Chemical structure
Properties
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Chemical name
(SP-4-2)-Diamminedichloroplatinum -
Molecular weight
300.05 -
Molecular formula
Cl2H6N2Pt -
PubChem identifier
441203 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 5 mM (with sonication) and in 0.9% w/w NaCl to 5 mM (with sonication) -
Handling
Unstable; make up solutions fresh and use immediately.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
N.N.Cl[Pt+2]Cl -
Source
Synthetic
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Research areas
Images
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Chemical Structure - Cisplatin, antineoplastic agent (ab141398)2D chemical structure image of ab141398, Cisplatin, antineoplastic agent
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (7)
ab141398 has been referenced in 7 publications.
- Tröndle K et al. Deep Learning-Assisted Nephrotoxicity Testing with Bioprinted Renal Spheroids. Int J Bioprint 8:528 (2022). PubMed: 35702333
- Mahmood N et al. S-adenosylmethionine in combination with decitabine shows enhanced anti-cancer effects in repressing breast cancer growth and metastasis. J Cell Mol Med 24:10322-10337 (2020). PubMed: 32720467
- Luo R et al. Cisplatin Facilitates Radiation-Induced Abscopal Effects in Conjunction with PD-1 Checkpoint Blockade Through CXCR3/CXCL10-Mediated T-cell Recruitment. Clin Cancer Res 25:7243-7255 (2019). PubMed: 31506388
- Tan Z et al. Environmental stresses induce karyotypic instability in colorectal cancer cells. Mol Biol Cell 30:42-55 (2019). PubMed: 30379607
- Carter RJ et al. Exploring the potential of BH3 mimetic therapy in squamous cell carcinoma of the head and neck. Cell Death Dis 10:912 (2019). PubMed: 31801952
- Qin W et al. Inhibiting microRNA-449 Attenuates Cisplatin-Induced Injury in NRK-52E Cells Possibly via Regulating the SIRT1/P53/BAX Pathway. Med Sci Monit 22:818-23 (2016). PubMed: 26968221
- Black JC et al. Regulation of Transient Site-specific Copy Gain by MicroRNA. J Biol Chem 291:4862-71 (2016). PubMed: 26755726