CTAP, mu opioid antagonist (ab120680)
Key features and details
- Potent, selective μ opioid antagonist
- CAS Number: 103429-32-9
- Soluble in water
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
CTAP, mu opioid antagonist -
Description
Potent, selective μ opioid antagonist -
Biological description
Potent and selective μ opioid receptor antagonist (1200-fold more selective vs. δ receptor). Blood-brain barrier permeable and active in vivo. Antagonizes antinociceptive effect.
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CAS Number
103429-32-9 -
Chemical structure
Properties
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Molecular weight
1104.31 -
Molecular formula
C51H69N13O11S2 -
Sequence
FCYWRTXT (Modifications: C-terminal amide; X-7 = Pen; Phe-1 = D-Phr; Trp-4 = D-Trp; Disulfide bonds: 2-7) -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water -
Handling
This product is supplied in one (or more) pack size which is freeze dried. Therefore the contents may not be readily visible, as they can coat the bottom or walls of the vial. Please see our FAQs and information page for more details on handling.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (1)
ab120680 has been referenced in 1 publication.
- Furukawa A et al. Endothelin Signaling Contributes to Modulation of Nociception in Early-stage Tongue Cancer in Rats. Anesthesiology 128:1207-1219 (2018). PubMed: 29461271