Diltiazem, L-type Ca2+ channel antagonist (ab120260)
Key features and details
- L-type Ca2+ channel antagonist
- CAS Number: 33286-22-5
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Diltiazem, L-type Ca2+ channel antagonist -
Description
L-type Ca2+ channel antagonist -
Biological description
L-type Ca2+ channel antagonist. Coronary vasodilator.
Also available in simple stock solutions (ab146694) - add 1 ml of water to get an exact, ready-to-use concentration. -
CAS Number
33286-22-5 -
Chemical structure
Properties
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Chemical name
(2S,3S)-(+)-cis-3-Acetoxy-5-(2-dimethylaminoethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one hydrochloride -
Molecular weight
450.98 -
Molecular formula
C22H26N2O4S.HCl -
PubChem identifier
62920 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.CN(C)CCN2c3ccccc3S[C@@H](c1ccc(OC)cc1)[C@@H](OC(C)=O)C2=O -
Source
Synthetic
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Research areas
Images
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Chemical Structure - Diltiazem, L-type Ca2+ channel antagonist (ab120260)2D chemical structure image of ab120260, Diltiazem, L-type Ca2+ channel antagonist
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (1)
ab120260 has been referenced in 1 publication.
- Das S et al. Redefining the role of Ca2+-permeable channels in photoreceptor degeneration using diltiazem. Cell Death Dis 13:47 (2022). PubMed: 35013127