Disuccinimidyl suberate, cross-linking reagent (ab141274)
Key features and details
- Homobifunctional primary amine reactive cross-linker
- CAS Number: 68528-80-3
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameDisuccinimidyl suberate, cross-linking reagent
DescriptionHomobifunctional primary amine reactive cross-linker
Homobifunctional primary amine reactive cross-linker. Contains an 8 atom linker (11.4 Å) and can cross-link distances up to ~25 Å due to protein flexibility. Produces no toxic side products.
Chemical nameOctanedioic acid 1,8-bis(2,5-dioxo-1-pyrrolidinyl) ester
Storage instructionsStore at +4°C. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141274 has been referenced in 2 publications.
- Xu G et al. Echinatin effectively protects against NLRP3 inflammasome-driven diseases by targeting HSP90. JCI Insight 6:N/A (2021). PubMed: 33350984
- Ma J et al. SARS-CoV-2 nucleocapsid suppresses host pyroptosis by blocking Gasdermin D cleavage. EMBO J 40:e108249 (2021). PubMed: 34296442