Key features and details
- Potent and selective PDGFRβ inhibitor
- CAS Number: 1123491-15-5
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameDMPQ dihydrochloride, PDGFR beta inhibitor
DescriptionPotent and selective PDGFRβ inhibitor
Potent and selective β-type platelet derived growth factor receptor tyrosine kinase (PDGFRβ) inhibitor (IC50 = 80 nM). Shows >100-fold selectivity over EGFR, PKA, PKC, p56 and erbB2.
Also available in simple stock solutions (ab146732) - add 1 ml of water to get an exact, ready-to-use concentration.
Chemical name5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Receptors & Transporters
- Enzyme-Linked Receptors
- Receptor tyrosine kinases
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141269 has not yet been referenced specifically in any publications.