Key features and details
- Histamine H1 receptor antagonist
- CAS Number: 90729-43-4
- Purity: > 98%
- Soluble in DMSO to 10 mM
- Form / State: Solid
- Source: Synthetic
Product nameEbastine, Histamine H1 receptor antagonist
DescriptionHistamine H1 receptor antagonist
Biological descriptionHistamine H1 receptor antagonist. Does not penetrate the blood-brain barrier. A CYP2J substrate, metabolized into carebastine via hydroxyebastine in vivo.
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 10 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Cholesterol Metabolism
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141928 has been referenced in 1 publication.
- Li Q et al. Antihistamine Drug Ebastine Inhibits Cancer Growth by Targeting Polycomb Group Protein EZH2. Mol Cancer Ther 19:2023-2033 (2020). PubMed: 32855270