FCCP, mitochondrial oxidative phosphorylation uncoupler (DMSO solution) (ab147482)
Key features and details
- Potent mitochondrial oxidative phosphorylation uncoupler
- CAS Number: 370-86-5
- Supplied in DMSO (50 mM)
- Form / State: Liquid
- Source: Synthetic
Overview
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Product name
FCCP, mitochondrial oxidative phosphorylation uncoupler (DMSO solution) -
Description
Potent mitochondrial oxidative phosphorylation uncoupler -
Biological description
Potent mitochondrial oxidative phosphorylation uncoupler (IC50 = 20 nM). Disrupts ATP synthesis by transporting protons across mitochondrial inner membranes. Depolarises mitochondrial membrane potential.
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CAS Number
370-86-5 -
Chemical structure
Properties
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Chemical name
Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone -
Molecular weight
254.17 -
Molecular formula
C10H5F3N4O -
PubChem identifier
330 -
Storage instructions
Shipped at Room Temperature. Store at -20°C long term. -
Solubility overview
Supplied in DMSO (50 mM) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
FC(F)(F)Oc1ccc(cc1)NN=C(/C#N)C#N -
Source
Synthetic
Associated products
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Alternative Versions
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab147482 has not yet been referenced specifically in any publications.