G3335, PPARgamma antagonist. (ab142179)
Key features and details
- Selective, cell-permeable, reversible PPARγ antagonist.
- CAS Number: 36099-95-3
- Purity: > 97%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameG3335, PPARgamma antagonist.
DescriptionSelective, cell-permeable, reversible PPARγ antagonist.
This product is manufactured by BioVision, an Abcam company and was previously called 1979 PPAR? Antagonist, G3335. 1979-25 is the same size as the 25 mg size of ab142179.
Chemical name2-[[2-Amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
ab142179 has been referenced in 3 publications.
- Hu L et al. Rosiglitazone ameliorates radiation-induced intestinal inflammation in rats by inhibiting NLRP3 inflammasome and TNF-a production. J Radiat Res 61:842-850 (2020). PubMed: 32876675
- Meng QQ et al. PPAR-? Activation Exerts an Anti-inflammatory Effect by Suppressing the NLRP3 Inflammasome in Spinal Cord-Derived Neurons. Mediators Inflamm 2019:6386729 (2019). PubMed: 31015796
- Meng QQ et al. Combined Rosiglitazone and Forskolin Have Neuroprotective Effects in SD Rats after Spinal Cord Injury. PPAR Res 2018:3897478 (2018). PubMed: 30034460