Gemfibrozil, PPARalpha activator (ab142883)
Key features and details
- PPARα activator
- CAS Number: 25812-30-0
- Purity: > 98%
- Soluble in DMSO to 100 mM (with warming) and in ethanol to 100 mM (with warming)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Gemfibrozil, PPARalpha activator -
Description
PPARα activator -
Purity
> 98% -
CAS Number
25812-30-0 -
Chemical structure
Properties
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Chemical name
5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic acid -
Molecular weight
250.33 -
Molecular formula
C15H22O3 -
PubChem identifier
3463 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM (with warming) and in ethanol to 100 mM (with warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=CC(=C(C=C1)C)OCCCC(C)(C)C(=O)O -
Source
Synthetic
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Research areas
Images
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Chemical Structure - Gemfibrozil, PPARalpha activator (ab142883)2D chemical structure image of ab142883, Gemfibrozil, PPARalpha activator
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab142883 has been referenced in 2 publications.
- Ding Y et al. Carnitine palmitoyltransferase 1 (CPT1) alleviates oxidative stress and apoptosis of hippocampal neuron in response to beta-Amyloid peptide fragment Aß25-35. Bioengineered 12:5440-5449 (2021). PubMed: 34424821
- Luo R et al. Activation of PPARA-mediated autophagy reduces Alzheimer disease-like pathology and cognitive decline in a murine model. Autophagy 16:52-69 (2020). PubMed: 30898012