Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate (ab146529)
![Chemical Structure - Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate (ab146529)](https://www.abcam.com/ps/products/146/ab146529/Images/ab146529-1-ab146529-Guanosine-539diphosphate-GDP-disodium-salt-Structure-CAS-7415692.jpg "Chemical Structure - Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate (ab146529)")
Key features and details
- Nucleoside diphosphate.
- CAS Number: 7415-69-2
- Purity: > 98%
Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate -
Description
Nucleoside diphosphate. -
Alternative names
- GDP disodium salt
- GDP-Na3
- Guanosine 5'-diphosphate disodium salt
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Biological description
Nucleoside diphosphate used as a substrate of pyruvate kinase to produce GTP in support of RNA biosynthesis. Used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Also used to study cell signaling processes mediate by guanine nucleotide exchange factors.
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Purity
> 98% -
CAS Number
7415-69-2 -
Chemical structure
Properties
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Molecular weight
487.17 -
Molecular formula
C10H13N5Na2O11P2 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM
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Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
Images
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Chemical Structure - Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate (ab146529)2D chemical structure image of ab146529, Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (4)
ab146529 has been referenced in 4 publications.
- Lattao R et al. Mauve/LYST limits fusion of lysosome-related organelles and promotes centrosomal recruitment of microtubule nucleating proteins. Dev Cell N/A:N/A (2021). PubMed: 33725482
- Kutsch M et al. Direct binding of polymeric GBP1 to LPS disrupts bacterial cell envelope functions. EMBO J 39:e104926 (2020). PubMed: 32510692
- Kovalski JR et al. The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2. Mol Cell 73:830-844.e12 (2019). PubMed: 30639242
- Kumar S et al. Mechanism of Stx17 recruitment to autophagosomes via IRGM and mammalian Atg8 proteins. J Cell Biol 217:997-1013 (2018). PubMed: 29420192