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    products/biochemicals/indomethacin-non-selective-cox-inhibitor-ab120719.pdf

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Biochemicals Chemical Type Biochemicals
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Indomethacin, Non-selective COX inhibitor (ab120719)

  • Datasheet
  • SDS
  • COA
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Chemical Structure - Indomethacin, Non-selective COX inhibitor (ab120719)

    Key features and details

    • Non-selective COX inhibitor
    • CAS Number: 53-86-1
    • Purity: > 99%
    • Soluble in DMSO to 100 mM and in ethanol to 50 mM (with warming)
    • Form / State: Solid
    • Source: Synthetic

    Overview

    • Product name

      Indomethacin, Non-selective COX inhibitor
    • Description

      Non-selective COX inhibitor
    • Biological description

      Non-selective COX inhibitor (IC50 = 230 and 630 nM for human COX-1 and COX-2, respectively). Activates PPARα and PPARγ (EC50 = 40 nM).

    • Purity

      > 99%
    • CAS Number

      53-86-1
    • Chemical structure

      Chemical Structure

    Properties

    • Chemical name

      1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid
    • Molecular weight

      357.79
    • Molecular formula

      C19H16ClNO4
    • Storage instructions

      Store at Room Temperature. The product can be stored for up to 12 months.
    • Solubility overview

      Soluble in DMSO to 100 mM and in ethanol to 50 mM (with warming)
    • Handling

      Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

      Toxic, refer to SDS for further information.

      Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

    • Source

      Synthetic

    • Research areas

      • Biochemicals
      • Chemical Type
      • Biochemicals
      • Biochemicals
      • Pharmacology
      • Receptors & Transporters
      • Nuclear Receptors
      • PPAR
      • Biochemicals
      • Pharmacology
      • Enzymes
      • Cyclooxygenase
      • Inhibitors
      • Metabolism
      • Pathways and Processes
      • Metabolic signaling pathways
      • Lipid and lipoprotein metabolism
      • Cholesterol Metabolism
      • Metabolism
      • Pathways and Processes
      • Metabolism processes
      • Hypoxia
      • Biochemicals
      • Research Area
      • Cancer
      • Nuclear Receptors
      • PPAR
      • Biochemicals
      • Research Area
      • Heart disease
      • Nuclear Receptors
      • PPAR
      • Biochemicals
      • Research Area
      • Hypertension
      • Nuclear Receptors
      • PPAR
      • Biochemicals
      • Research Area
      • Stroke
      • Nuclear Receptors
      • PPAR
      • Biochemicals
      • Pharmacology
      • Signaling
      • Lipid signaling
      • Prostaglandins

    Associated products

    • Related Products

      • PPAR gamma Transcription Factor Assay Kit (ab133101)
      • PPAR delta Transcription Factor Assay Kit (ab133106)
      • PPAR alpha Transcription Factor Assay Kit (ab133107)
      • PPAR (alpha, delta, gamma) Transcription Factor Assay Kit (ab133113)

    Images

    • Chemical Structure - Indomethacin, Non-selective COX inhibitor (ab120719)
      Chemical Structure - Indomethacin, Non-selective COX inhibitor (ab120719)
      2D chemical structure image of ab120719, Indomethacin, Non-selective COX inhibitor

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download
    • COA

    References (0)

    Publishing research using ab120719? Please let us know so that we can cite the reference in this datasheet.

    ab120719 has not yet been referenced specifically in any publications.

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