Key features and details
- Non-selective COX inhibitor
- CAS Number: 53-86-1
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 50 mM (with warming)
- Form / State: Solid
- Source: Synthetic
Product nameIndomethacin, Non-selective COX inhibitor
DescriptionNon-selective COX inhibitor
Non-selective COX inhibitor (IC50 = 230 and 630 nM for human COX-1 and COX-2, respectively). Activates PPARα and PPARγ (EC50 = 40 nM).
Chemical name1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM and in ethanol to 50 mM (with warming)
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Cholesterol Metabolism
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120719 has not yet been referenced specifically in any publications.