IOX-1, histone demethylase JMJD inhibitor (ab144394)
Key features and details
- Cell permeable histone demethylase JMJD inhibitor
- CAS Number: 5852-78-8
- Purity: > 99%
- Soluble in DMSO to 100 mM and in 2eq. NaOH to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
IOX-1, histone demethylase JMJD inhibitor -
Description
Cell permeable histone demethylase JMJD inhibitor -
Alternative names
- 5-carboxy-8HQ
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Purity
> 99% -
CAS Number
5852-78-8 -
Chemical structure
Properties
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Chemical name
8-Hydroxyquinoline-5-carboxylic acid -
Molecular weight
189.17 -
Molecular formula
C10H7NO3 -
PubChem identifier
459617 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in 2eq. NaOH to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
c1cc2c(ccc(c2nc1)O)C(O)=O -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (1)
ab144394 has been referenced in 1 publication.
- Unemura K et al. A neuronal cell-based reporter system for monitoring the activity of HDAC2. SLAS Discov 27:440-447 (2022). PubMed: 36240996