Isradipine, L-type Ca2+ channel blocker (ab120142)
Key features and details
- L-type Ca2+ channel blocker
- CAS Number: 75695-93-1
- Soluble in DMSO to 100 mM and in ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Isradipine, L-type Ca2+ channel blocker -
Description
L-type Ca2+ channel blocker -
Biological description
L-type Ca2+ channel blocker.
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CAS Number
75695-93-1 -
Chemical structure
Properties
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Chemical name
4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid methyl 1-methylethyl ester -
Molecular weight
371.39 -
Molecular formula
C19H21N3O5 -
PubChem identifier
3784 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C(OC)C3=C(C)NC(C)=C(C(=O)OC(C)C)C3c1cccc2nonc12 -
Source
Synthetic
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Research areas
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Retinoic & Retinoid
- Epigenetics and Nuclear Signaling
- Nuclear Signaling Pathways
- Nuclear Receptors
- Orphan Nuclear Receptors
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipases
Images
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Chemical Structure - Isradipine, L-type Ca2+ channel blocker (ab120142)2D chemical structure image of ab120142, Isradipine, L-type Ca2+ channel blocker
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (3)
ab120142 has been referenced in 3 publications.
- Meyer DJ et al. The Na+/K+ pump dominates control of glycolysis in hippocampal dentate granule cells. Elife 11:N/A (2022). PubMed: 36222651
- Díaz-García CM et al. The distinct roles of calcium in rapid control of neuronal glycolysis and the tricarboxylic acid cycle. Elife 10:N/A (2021). PubMed: 33555254
- Jurkovicová-Tarabová B et al. Repertoire of high voltage-activated Ca2+ channels in the lateral superior olive: functional analysis in wild-type, Ca(v)1.3(-/-), and Ca(v)1.2DHP(-/-) mice. J Neurophysiol 108:365-79 (2012). PubMed: 22539826