JC-1, Mitochondrial membrane potential dye (ab141387)
Key features and details
- Mitochondrial membrane-potential dye
- CAS Number: 3520-43-2
- Purity: > 98%
- Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Product nameJC-1, Mitochondrial membrane potential dye
DescriptionMitochondrial membrane-potential dye
Chemical name5,6-Dichloro-2-[(E)-3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2H-benzimidazol-2-ylidene)-1-prop-1-enyl]-1,3-diethyl-1H-benzimidazolium iodide
Storage instructionsShipped at 4°C. Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 25 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
ab141387 has been referenced in 17 publications.
- Ding J et al. HADHA alleviates hepatic steatosis and oxidative stress in NAFLD via inactivation of the MKK3/MAPK pathway. Mol Biol Rep 50:961-970 (2023). PubMed: 36376538
- Dong X et al. Inhibition of miR-421 Preserves Mitochondrial Function and Protects against Parkinson's Disease Pathogenesis via Pink1/Parkin-Dependent Mitophagy. Dis Markers 2022:5186252 (2022). PubMed: 35664430
- Rodríguez-Nuevo A et al. Oocytes maintain ROS-free mitochondrial metabolism by suppressing complex I. Nature 607:756-761 (2022). PubMed: 35859172
- Chen J et al. Inhibition of Autophagy Prevents Panax Notoginseng Saponins (PNS) Protection on Cardiac Myocytes Against Endoplasmic Reticulum (ER) Stress-Induced Mitochondrial Injury, Ca2+ Homeostasis and Associated Apoptosis. Front Pharmacol 12:620812 (2021). PubMed: 33762943
- Britti E et al. Calcitriol increases frataxin levels and restores mitochondrial function in cell models of Friedreich Ataxia. Biochem J 478:1-20 (2021). PubMed: 33305808