Manumycin A, Ras farnesyltransferase inhibitor (ab144297)
Key features and details
- Potent, selective, competitive cell-permeable Ras farnesyltransferase inhibitor
- CAS Number: 52665-74-4
- Purity: > 96%
- Soluble in DMSO to 10 mM
- Form / State: Solid
- Source: Streptomyces parvulus
Overview
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Product name
Manumycin A, Ras farnesyltransferase inhibitor -
Description
Potent, selective, competitive cell-permeable Ras farnesyltransferase inhibitor -
Purity
> 96% -
CAS Number
52665-74-4 -
Chemical structure
Properties
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Chemical name
(2E,4E,6R)-N-[(1S,5S,6R)-5-Hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopenten-1-yl)amino]-7-oxohepta-1,3,5-trienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-2,4,6-trimethyldeca-2,4-dienamide -
Molecular weight
550.64 -
Molecular formula
C31H38N2O7 -
PubChem identifier
6438330 -
Storage instructions
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in DMSO to 10 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCC[C@@H](C)/C=C(\C)/C=C(\C)/C(=O)NC1=C[C@]([C@H]2[C@@H](C1=O)O2)(/C=C/C=C/C=C/C(=O)NC3=C(CCC3=O)O)O -
Source
Streptomyces parvulus
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Research areas
Images
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Chemical Structure - Manumycin A, Ras farnesyltransferase inhibitor (ab144297)2D chemical structure image of ab144297, Manumycin A, Ras farnesyltransferase inhibitor
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab144297 has not yet been referenced specifically in any publications.