Menadione, Phosphatase inhibitor (ab141272)
Key features and details
- Phosphatase inhibitor; vitamin K prodrug
- CAS Number: 58-27-5
- Purity: > 99%
- Soluble in DMSO to 100 mM and ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Menadione, Phosphatase inhibitor -
Description
Phosphatase inhibitor; vitamin K prodrug -
Biological description
Vitamin K produg able to inhibit protein tyrosine phosphatases and induce DNA strand breaks. Able to prevent erlotinib (ab120881) induced cell-cycle arrest. Generates ROS°. Active in vivo.
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Purity
> 99% -
CAS Number
58-27-5 -
Chemical structure
Properties
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Chemical name
2-Methyl-1,4-naphthoquinone -
Molecular weight
172.18 -
Molecular formula
C11H8O2 -
PubChem identifier
4055 -
Storage instructions
Store at Room Temperature. Store In the Dark. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and ethanol to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C2C=C(C)C(=O)c1ccccc12 -
Source
Synthetic
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Research areas
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab141272 has not yet been referenced specifically in any publications.