Mirtazapine, alpha2, 5-HT2, 5-HT3 antagonist (ab120068)
Key features and details
- Antidepressant. α2, 5-HT2, 5-HT3 antagonist.
- CAS Number: 85650-52-8
- Soluble in DMSO to 20 mM and in ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Mirtazapine, alpha2, 5-HT2, 5-HT3 antagonist -
Description
Antidepressant. α2, 5-HT2, 5-HT3 antagonist. -
Alternative names
- 6-Azamianserin
- Org3770
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Biological description
Antagonist at α2, 5-HT2 and 5-HT3 receptors. Antidepressant in vivo.
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CAS Number
85650-52-8 -
Chemical structure
Properties
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Chemical name
1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c]benzazepine -
Molecular weight
265.35 -
Molecular formula
C17H19N3 -
PubChem identifier
4205 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 20 mM and in ethanol to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN1CC2N(CC1)c4ncccc4Cc3ccccc23 -
Source
Synthetic
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Research areas
Images
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Chemical Structure - Mirtazapine, alpha2, 5-HT2, 5-HT3 antagonist (ab120068)2D chemical structure image of ab120068, Mirtazapine, alpha2, 5-HT2, 5-HT3 antagonist
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (2)
ab120068 has been referenced in 2 publications.
- Nerli E et al. In vitro modeling of dendritic atrophy in Rett syndrome: determinants for phenotypic drug screening in neurodevelopmental disorders. Sci Rep 10:2491 (2020). PubMed: 32051524
- Flores Gutiérrez J et al. Protective role of mirtazapine in adult female Mecp2+/- mice and patients with Rett syndrome. J Neurodev Disord 12:26 (2020). PubMed: 32988385