Muscimol, GABAA agonist (ab120094)
Key features and details
- Potent, selective GABAA agonist
- CAS Number: 2763-96-4
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Muscimol, GABAA agonist -
Description
Potent, selective GABAA agonist -
Biological description
Potent, selective GABAA agonist.
Also available in simple stock solutions (ab146673) - add 1 ml of water to get an exact, ready-to-use concentration. -
CAS Number
2763-96-4 -
Chemical structure
Properties
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Chemical name
5-(Aminomethyl)isoxazol-3-ol -
Molecular weight
114.10 -
Molecular formula
C4H6N2O2 -
PubChem identifier
4266 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
NCc1cc(O)no1 -
Source
Synthetic
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Research areas
Images
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Chemical Structure - Muscimol, GABAA agonist (ab120094)2D chemical structure image of ab120094, Muscimol, GABAA agonist
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (20)
ab120094 has been referenced in 20 publications.
- Sibille J et al. High-density electrode recordings reveal strong and specific connections between retinal ganglion cells and midbrain neurons. Nat Commun 13:5218 (2022). PubMed: 36064789
- Pisupati S et al. Lapses in perceptual decisions reflect exploration. Elife 10:N/A (2021). PubMed: 33427198
- Yao JD et al. Parietal Cortex Is Required for the Integration of Acoustic Evidence. Curr Biol 30:3293-3303.e4 (2020). PubMed: 32619478
- Estebanez L et al. Parvalbumin-Expressing GABAergic Neurons in Primary Motor Cortex Signal Reaching. Cell Rep 20:308-318 (2017). PubMed: 28700934
- Koga K et al. Chemogenetic silencing of GABAergic dorsal horn interneurons induces morphine-resistant spontaneous nocifensive behaviours. Sci Rep 7:4739 (2017). PubMed: 28680103