Nomega-Nitro-L-arginine (L-NNA), Nitric oxide synthase inhibitor (ab141312)
Key features and details
- Nitric oxide synthase inhibitor
- CAS Number: 2149-70-4
- Purity: > 99%
- Soluble in water to 5 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Nomega-Nitro-L-arginine (L-NNA), Nitric oxide synthase inhibitor -
Description
Nitric oxide synthase inhibitor -
Alternative names
- L-NNA
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Biological description
Nitric oxide synthase inhibitor (Ki = 4.4 μM). Cardiovascular effects. Active in vivo.
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Purity
> 99% -
CAS Number
2149-70-4 -
Chemical structure
Properties
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Chemical name
Nω-Nitro-L-arginine -
Molecular weight
219.20 -
Molecular formula
C6H13N5O4 -
PubChem identifier
440005 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 5 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
N[C@@H](CCCNC(=N)N[N+]([O-])=O)C(=O)O -
Source
Synthetic
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Research areas
- Biochemicals
- Pharmacology
- Signaling
- Signal transduction
- Nitric oxide & oxidative stress
- NOS
- Inhibitors
- Biochemicals
- Research Area
- Alzheimer's Disease
- Signaling
- Signal transduction
- Nitric oxide signaling
- NOS
- Inhibitors
- Biochemicals
- Research Area
- Diabetes
- Signaling
- Signal transduction
- Nitric oxide signaling
- NOS
- Inhibitors
- Biochemicals
- Research Area
- Hypertension
- Signaling
- Signal transduction
- Nitric oxide signaling
- NOS
- Inhibitors
- Biochemicals
- Research Area
- Obesity
- Signaling
- Signal transduction
- Nitric oxide signaling
- NOS
- Inhibitors
Images
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Chemical Structure - Nomega-Nitro-L-arginine (L-NNA), Nitric oxide synthase inhibitor (ab141312)2D chemical structure image of ab141312, Nomega-Nitro-L-arginine (L-NNA), Nitric oxide synthase inhibitor
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (3)
ab141312 has been referenced in 3 publications.
- Al-Shboul OA et al. Changes in Gastric Smooth Muscle Cell Contraction during Pregnancy: Effect of Estrogen. J Pregnancy 2019:4302309 (2019). PubMed: 31080672
- Al-Shboul OA et al. Estrogen relaxes gastric muscle cells via a nitric oxide- and cyclic guanosine monophosphate-dependent mechanism: A sex-associated differential effect. Exp Ther Med 16:1685-1692 (2018). PubMed: 30186388
- Al-Shboul OA et al. Effect of progesterone on nitric oxide/cyclic guanosine monophosphate signaling and contraction in gastric smooth muscle cells. Biomed Rep 9:511-516 (2018). PubMed: 30546879