PD 168568 dihydrochloride, D4 antagonist (ab120611)
Key features and details
- Potent and selective D4 antagonist
- CAS Number: 210688-56-5
- Purity: > 99%
- Soluble in water to 50 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product namePD 168568 dihydrochloride, D4 antagonist
DescriptionPotent and selective D4 antagonist
Potent and selective D4 antagonist (Ki = 8.8 nM at D4, and 1842 nM at D2). Inhibits amphetamine stimulated locomotor activity in vivo; orally active.
Chemical name3-[2-[4-(3,4-dimethylphenyl)-1-piperazinyl]ethyl]-2,3-dihydro-1H-isoindol-1-one dihydrochloride
Storage instructionsStore at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 50 mM and in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120611 has been referenced in 1 publication.
- Chen X et al. Purification, characterization and in vitro and in vivo immune enhancement of polysaccharides from mulberry leaves. PLoS One 14:e0208611 (2019). PubMed: 30601811