Key features and details
- PKC activator (DMSO solution)
- CAS Number: 16561-29-8
- Purity: > 98%
- Supplied in DMSO (10mM)
- Form / State: Liquid
- Source: Synthetic
Product namePhorbol 12-myristate 13-acetate (PMA), PKC activator (DMSO solution)
DescriptionPKC activator (DMSO solution)
Potent nanomolar activator of protein kinase C in vivo and in vitro. Binds to C1 domain of protein kinase C, induces membrane translocation and enzyme activation. Also reported to have actions on non-kinase proteins including chimaerins, RasGRP and Unc-13/Munc-13. Extremely potent mouse skin tumor promoter.
Chemical namePhorbol 12-myristate 13-acetate
Storage instructionsShipped at room temperature. Store at -20°C.
Solubility overviewSupplied in DMSO (10mM)
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further instruction.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab147465 has not yet been referenced specifically in any publications.