Key features and details
- 5-HT1A and 5-HT1B receptor antagonist
- CAS Number: 13523-86-9
- Soluble in DMSO to 50 mM and in ethanol to 25 mM (with heating)
- Form / State: Solid
- Source: Synthetic
Product namePindolol, 5-HT1A and 5-HT1B receptor antagonist
Description5-HT1A and 5-HT1B receptor antagonist
5-HT1A and 5-HT1B receptor antagonist (Ki and IC50 values are 8.9 and 6.8 nM at 5-HT1A and 5-HT1B receptors, respectively). Partial β3 adrenoceptor agonist (pEC50 = 5.11). Accelerates antidepressant effects of selective serotonin reuptake inhibitors (SSRIs).
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 50 mM and in ethanol to 25 mM (with heating)
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Cholesterol Metabolism
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120521 has not yet been referenced specifically in any publications.