Procainamide hydrochloride, Sodium channel blocker (ab120955)
Key features and details
- Sodium channel blocker. Specific DNA methyltransferase 1 inhibitor.
- CAS Number: 614-39-1
- Purity: > 99%
- Soluble in water to 100 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameProcainamide hydrochloride, Sodium channel blocker
DescriptionSodium channel blocker. Specific DNA methyltransferase 1 inhibitor.
Sodium channel blocker. Specific DNA methyltransferase 1 inhibitor (Ki = 7.2 μM). Antiarrhythmic in vivo. Limited ability to cross the blood-brain barrier.
Chemical name4-Amino-N-(2-diethylaminoethyl)benzamide hydrochloride
Storage instructionsStore at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 100 mM and in ethanol to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120955 has been referenced in 3 publications.
- Seabright GE et al. Networks of HIV-1 Envelope Glycans Maintain Antibody Epitopes in the Face of Glycan Additions and Deletions. Structure 28:897-909.e6 (2020). PubMed: 32433992
- Struwe WB et al. Site-Specific Glycosylation of Virion-Derived HIV-1 Env Is Mimicked by a Soluble Trimeric Immunogen. Cell Rep 24:1958-1966.e5 (2018). PubMed: 30134158
- Hasan SS et al. Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization. Cell Rep 25:3136-3147.e5 (2018). PubMed: 30540945