Key features and details
- Aminonuclease antibiotic agent. Protein biosynthesis inhibitor.
- CAS Number: 58-58-2
- Purity: > 98%
- Soluble in water to 75 mM
- Form / State: Solid
- Source: Synthetic
Product namePuromycin dihydrochloride, Protein biosynthesis inhibitor
DescriptionAminonuclease antibiotic agent. Protein biosynthesis inhibitor.
This product is manufactured by BioVision, an Abcam company and was previously called 1860 Puromycin Dihydrochloride. 1860-250 is the same size as the 250 mg size of ab141453.
Chemical name(2S)-2-Amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide dihydrochloride
Storage instructionsStore at -20°C (desiccating conditions).
Solubility overviewSoluble in water to 75 mM
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141453 has been referenced in 2 publications.
- Hu J et al. Hexosamine biosynthetic pathway promotes the antiviral activity of SAMHD1 by enhancing O-GlcNAc transferase-mediated protein O-GlcNAcylation. Theranostics 11:805-823 (2021). PubMed: 33391506
- Gao Q et al. SLC27A5 deficiency activates NRF2/TXNRD1 pathway by increased lipid peroxidation in HCC. Cell Death Differ N/A:N/A (2019). PubMed: 31367013