Key features and details
- Cell-permeable, selective A3 receptor antagonist. Potent MPS1 inhibitor.
- CAS Number: 656820-32-5
- Purity: > 98%
- Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Product nameReversine, Cell-permeable A3 receptor antagonist
DescriptionCell-permeable, selective A3 receptor antagonist. Potent MPS1 inhibitor.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 25 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120921 has been referenced in 3 publications.
- Aldaz P et al. Identification of a Dexamethasone Mediated Radioprotection Mechanism Reveals New Therapeutic Vulnerabilities in Glioblastoma. Cancers (Basel) 13:N/A (2021). PubMed: 33478100
- Xian S et al. The unfolded protein response links tumor aneuploidy to local immune dysregulation. EMBO Rep 22:e52509 (2021). PubMed: 34698427
- French BT & Straight AF CDK phosphorylation of Xenopus laevis M18BP1 promotes its metaphase centromere localization. EMBO J 38:N/A (2019). PubMed: 30606714