RGDS peptide, Fibronectin inhibitor (ab230365)
Key features and details
- Fibronectin inhibitor
- CAS Number: 91037-65-9
- Purity: > 95%
30, 25 and 50 mg/ml in ethanol, DMSO and dimethyl formamide respectively, and 10 mg/ml in PBS (pH 7.2).
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
RGDS peptide, Fibronectin inhibitor -
Description
Fibronectin inhibitor -
Alternative names
- Fibronectin inhibitor
- H-Arg-Gly-Asp-Ser-OH
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Biological description
Conserved tetrapeptide sequence Arg-
Gly- Asp-Ser (RGDS) found on fibronectin, fibrinogen alpha and von Willebrand factor. Associates with integrins on the cell surface. Inhibits thrombin- induced binding of platelets to fibronectin, fibrinogen alpha and von Willebrand factor. -
Purity
> 95% -
CAS Number
91037-65-9 -
Chemical structure
Properties
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Chemical name
L-
arginylglycyl- L- α- aspartyl- L- serine -
Molecular weight
433.42 -
Molecular formula
C15H27N7O8 -
Sequence
L-Arginylglycyl-L-α-aspartyl-L-serine -
PubChem identifier
107775 -
Storage instructions
Shipped at 4°C. Store at -20°C. -
Solubility overview
30, 25 and 50 mg/ml in ethanol, DMSO and dimethyl formamide respectively, and 10 mg/ml in PBS (pH 7.2).
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Handling
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
[H]N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(O)=O -
Source
Synthetic
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Research areas
Images
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Chemical Structure - RGDS peptide, Fibronectin inhibitor (ab230365)2D chemical structure image of ab230365, RGDS peptide, Fibronectin inhibitor
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab230365 has been referenced in 1 publication.
- Zhao S et al. Sirtuin 1 Induces Choroidal Neovascularization and Triggers Age-Related Macular Degeneration by Promoting LCN2 through SOX9 Deacetylation. Oxid Med Cell Longev 2022:1671438 (2022). PubMed: 35720180