Rhodadyn™ B10, Negative control for Rhodadyn™ C10 (ab120796)
Key features and details
- Negative control for Rhodadyn™ C10 (ab120795)
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Rhodadyn™ B10, Negative control for Rhodadyn™ C10 -
Description
Negative control for Rhodadyn™ C10 (ab120795) -
Biological description
Negative control for Rhodadyn™ C10 (ab120795). Demonstrates no significant inhibition of dynamin I or dynamin II in vitro GTPase activity at concentrations up to 300 μM and has no effect on clathrin-mediated endocytosis of transferrin when applied for 30 minutes to U2OS cells in culture.
Robertson J et al. The rhodadyn™ a new class of small molecule inhibitors of dynamin GTPase. ACS Med. Chem (2012). -
Purity
> 98% -
General notes
Sold under exclusive licence from Children's Medical Research Institute and Newcastle Innovations Ltd. Rhodadyn™ is a trademark of Children's Medical Research Institute and Newcastle Innovation Ltd. -
Chemical structure
Properties
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Chemical name
(5Z)-5-[4-[3-(Dimethylamino)propoxy]benzylidene]-2-thioxo-1,3-thiazolidin-4-one -
Molecular weight
322.44 -
Molecular formula
C15H18N2O2S2 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Unstable; make up solutions fresh and use immediately.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas
Images
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Chemical Structure - Rhodadyn™ B10, Negative control for Rhodadyn™ C10 (ab120796)2D chemical structure image of ab120796, Rhodadyn™ B10, Negative control for Rhodadyn™ C10
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab120796 has not yet been referenced specifically in any publications.