Hello. We're improving abcam.com and we'd welcome your feedback.

Hello. We're improving abcam.com and we'd welcome your feedback.

Infomation icon

We haven't added this to the BETA yet

New BETA website

New BETA website

Hello. We're improving abcam.com and we'd welcome your feedback.

Take a look at our BETA site and see what we’ve done so far.

Switch on our new BETA site

Now available

Search and browse selected products

  • A selection of primary antibodies

Purchase these through your usual distributor

In the coming months

  • Additional product types
  • Supporting content
  • Sign in to your account
  • Purchase online

Rhodadyn™ C10, cell-permeable dynamin I inhibitor (ab120795)

Submit a review Submit a question
Chemical Structure - Rhodadyn™ C10, cell-permeable dynamin I inhibitor (ab120795)

    Key features and details

    • Highly potent cell-permeable dynamin I inhibitor
    • Purity: > 98%
    • Soluble in DMSO to 100 mM
    • Form / State: Solid
    • Source: Synthetic

    Overview

    • Product name

      Rhodadyn™ C10, cell-permeable dynamin I inhibitor

    • Description

      Highly potent cell-permeable dynamin I inhibitor

    • Biological description

      Highly potent cell-permeable dynamin I GTPase activity inhibitor (IC50 values are 7.1 and 30.3 μM at dynamin I and dynamin II, respectively). Blocks clathrin-mediated endocytosis of transferrin when applied for 30 minutes to U2OS cells in culture (IC50 = 7.0 μM).
      Rhodadyn™ B10 negative control also available (ab120796).

      Robertson J et al. The rhodadyn™ a new class of small molecule inhibitors of dynamin GTPase. ACS Med. Chem (2012).

    • Purity

      > 98%

    • General notes

      Sold under exclusive licence from Children's Medical Research Institute and Newcastle Innovations Ltd. Rhodadyn™ is a trademark of Children's Medical Research Institute and Newcastle Innovation Ltd.

    • Chemical structure

      Chemical Structure

    Properties

    Images

    • Chemical Structure - Rhodadyn™ C10, cell-permeable dynamin I inhibitor (ab120795)
      Chemical Structure - Rhodadyn™ C10, cell-permeable dynamin I inhibitor (ab120795)
      2D chemical structure image of ab120795, Rhodadyntrade C10, cell-permeable dynamin I inhibitor

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab120795? Please let us know so that we can cite the reference in this datasheet.

    ab120795 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    Show All Reviews Q&A
    Submit a review Submit a question

    There are currently no Customer reviews or Questions for ab120795.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
    For licensing inquiries, please contact partnerships@abcam.com