Rosiglitazone maleate (Avandia), PPARgamma agonist. Maleate salt. (ab142461)
Key features and details
- Potent, selective PPARγ agonist. Maleate salt.
- CAS Number: 155141-29-0
- Purity: > 98%
- Soluble in DMSO and ethanol
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Rosiglitazone maleate (Avandia), PPARgamma agonist. Maleate salt. -
Description
Potent, selective PPARγ agonist. Maleate salt. -
Purity
> 98% -
CAS Number
155141-29-0 -
Chemical structure
Properties
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Chemical name
5-[[4-[2-[Methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione maleate -
Molecular weight
473.51 -
Molecular formula
C18H19N3O3S.C4H4O4 -
PubChem identifier
5281055 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO and ethanol -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3.C(=CC(=O)O)C(=O)O -
Source
Synthetic
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Research areas
Images
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Chemical Structure - Rosiglitazone maleate (Avandia), PPARgamma agonist. Maleate salt. (ab142461)2D chemical structure image of ab142461, Rosiglitazone maleate (Avandia), PPARgamma agonist. Maleate salt.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (4)
ab142461 has been referenced in 4 publications.
- Aaron N et al. Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells. Elife 10:N/A (2021). PubMed: 34155972
- Liu L et al. PPAR? Deacetylation Confers the Antiatherogenic Effect and Improves Endothelial Function in Diabetes Treatment. Diabetes 69:1793-1803 (2020). PubMed: 32409492
- Chan M et al. Identification of a natural beige adipose depot in mice. J Biol Chem 294:6751-6761 (2019). PubMed: 30824545
- Kraakman MJ et al. PPAR? deacetylation dissociates thiazolidinedione's metabolic benefits from its adverse effects. J Clin Invest 128:2600-2612 (2018). PubMed: 29589839