(R,S)-CPP, NMDA antagonist (ab120160)
Key features and details
- Potent NMDA antagonist
- CAS Number: 100828-16-8
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
(R,S)-CPP, NMDA antagonist -
Description
Potent NMDA antagonist -
Biological description
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CAS Number
100828-16-8 -
Chemical structure
Properties
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Chemical name
(R,S)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid -
Molecular weight
252.20 -
Molecular formula
C8H17N2O5P -
PubChem identifier
1228 -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C(O)C1CN(CCCP(=O)(O)O)CCN1 -
Source
Synthetic
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Research areas
Images
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Chemical Structure - (R,S)-CPP, NMDA antagonist (ab120160)2D chemical structure image of ab120160, (R,S)-CPP, NMDA antagonist
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (5)
ab120160 has been referenced in 5 publications.
- Weyrer C et al. The Role of CaV2.1 Channel Facilitation in Synaptic Facilitation. Cell Rep 26:2289-2297.e3 (2019). PubMed: 30811980
- Turecek J & Regehr WG Neuronal Regulation of Fast Synaptotagmin Isoforms Controls the Relative Contributions of Synchronous and Asynchronous Release. Neuron 101:938-949.e4 (2019). PubMed: 30733150
- Han KS et al. Ephaptic Coupling Promotes Synchronous Firing of Cerebellar Purkinje Cells. Neuron 100:564-578.e3 (2018). PubMed: 30293822
- Armbruster M et al. Glutamate Clearance Is Locally Modulated by Presynaptic Neuronal Activity in the Cerebral Cortex. J Neurosci 36:10404-10415 (2016). PubMed: 27707974
- Cantu D et al. Traumatic Brain Injury Increases Cortical Glutamate Network Activity by Compromising GABAergic Control. Cereb Cortex : (2014). PubMed: 24610117