(R,S)-Sulpiride, D2-like dopamine receptor antagonist (ab120578)
Key features and details
- D2-like dopamine receptor antagonist
- CAS Number: 15676-16-1
- Soluble in DMSO to 100 mM and in 1 eq. HCl to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
(R,S)-Sulpiride, D2-like dopamine receptor antagonist -
Description
D2-like dopamine receptor antagonist -
Biological description
D2-like dopamine receptor antagonist. Shows antipsychotic activity. Active enantiomer (S)-sulpiride (ab120579) also available.
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CAS Number
15676-16-1 -
Chemical structure
Properties
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Chemical name
(R,S)-(±)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide -
Molecular weight
341.42 -
Molecular formula
C15H23N3O4S -
PubChem identifier
5355 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in 1 eq. HCl to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCN2CCCC2CNC(=O)c1cc(ccc1OC)S(N)(=O)=O -
Source
Synthetic
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Research areas
Associated products
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Related Products
Images
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Chemical Structure - (R,S)-Sulpiride, D2-like dopamine receptor antagonist (ab120578)2D chemical structure image of ab120578, (R,S)-Sulpiride, D2-like dopamine receptor antagonist
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (1)
ab120578 has been referenced in 1 publication.
- Blythe SN et al. Cellular mechanisms underlying burst firing in substantia nigra dopamine neurons. J Neurosci 29:15531-41 (2009). PubMed: 20007477