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    products/biochemicals/s-methyl-nn-diethylthiocarbamate-sulfone-medtc-aldehyde-dehydrogenase-inhibitor-ab144779.pdf

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Biochemicals Product Range New
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S-Methyl-N,N-diethylthiocarbamate Sulfone (MeDTC), aldehyde dehydrogenase inhibitor (ab144779)

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Key features and details

  • Potent irreversible inhibitor of low Km mitochondrial aldehyde dehydrogenase (ALDH)
  • CAS Number: 155514-79-7
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    S-Methyl-N,N-diethylthiocarbamate Sulfone (MeDTC), aldehyde dehydrogenase inhibitor
  • Description

    Potent irreversible inhibitor of low Km mitochondrial aldehyde dehydrogenase (ALDH)
  • Alternative names

    • MeDTC
  • Biological description

    Potent irreversible inhibitor of low Km mitochondrial aldehyde dehydrogenase (ALDH) (IC50 = 420 nM). Dioxygenated metabolite of disulfiram. Potential use in embryogenic studies and retinoic acid signaling. Active in vitro and in vivo.
  • CAS Number

    155514-79-7
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    N,N-Diethyl-1-methylsulfonylformamide
  • Molecular weight

    179.24
  • Molecular formula

    C6H13NO3S
  • PubChem identifier

    3552889
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCN(CC)C(=O)S(=O)(=O)C
  • Source

    Synthetic

  • Research areas

    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Nuclear Receptors
    • Retinoic acid receptors
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Dehydrogenase
    • Inhibitors

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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Datasheets and documents

  • SDS download

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References (0)

Publishing research using ab144779? Please let us know so that we can cite the reference in this datasheet.

ab144779 has not yet been referenced specifically in any publications.

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