(S)-Sulpiride, D2-like dopamine antagonist (ab120579)
Key features and details
- D2-like dopamine antagonist. Active enantiomer.
- CAS Number: 23672-07-3
- Soluble in DMSO to 100 mM and in ethanol to 25 mM (with warming)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
(S)-Sulpiride, D2-like dopamine antagonist -
Description
D2-like dopamine antagonist. Active enantiomer. -
Biological description
Selective D2-like dopamine antagonist (Ki values are ~ 0.015, ~ 0.013, and 1 μM at D2, D3, and D4 receptors, respectively). Active enantiomer of Sulpiride (ab120578). Antipsychotic and prokinetic agent.
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CAS Number
23672-07-3 -
Chemical structure
Properties
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Chemical name
(S)-(-)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide -
Molecular weight
341.42 -
Molecular formula
C15H23N3O4S -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 25 mM (with warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas
Associated products
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Related Products
Images
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Chemical Structure - (S)-Sulpiride, D2-like dopamine antagonist (ab120579)2D chemical structure image of ab120579, (S)-Sulpiride, D2-like dopamine antagonist
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (1)
ab120579 has been referenced in 1 publication.
- Nimitvilai S et al. Effects of monoamines on the intrinsic excitability of lateral orbitofrontal cortex neurons in alcohol-dependent and non-dependent female mice. Neuropharmacology 137:1-12 (2018). PubMed: 29689260