SAM e (S-(5-Adenosyl)-L-methionine disulfate tosylate), Methyl donor (ab142221)
Key features and details
- Methyl donor and cofactor for enzyme-catalyzed methylations
- CAS Number: 97540-22-2
- Purity: > 95%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
SAM e (S-(5-Adenosyl)-L-methionine disulfate tosylate), Methyl donor -
Description
Methyl donor and cofactor for enzyme-catalyzed methylations -
Purity
> 95% -
General notes
This product is manufactured by BioVision, an Abcam company and was previously called 2077 S-Adenosyl-L-methionine disulfate tosylate. 2077-100 is the same size as the 100 mg size of ab142221.
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CAS Number
97540-22-2 -
Chemical structure
Properties
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Chemical name
[(3S)-3-Amino-3-carboxypropyl]-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3, 4-dihydroxyoxolan-2-yl]methyl]methylsulfanium disulfate tosylate -
Molecular weight
766.78 -
Molecular formula
C15H22N6O5S.C7H8O3S.2H2SO4 -
PubChem identifier
163657 -
Storage instructions
Shipped at 4°C. Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=CC=C(C=C1)S(=O)(=O)[O-].C[S+](CCC(C(=O)O)N)CC1C(C(C(O1)N2C=NC3=C2N=CN=C3N)O)O.OS(=O)(=O)[O-].[O-]S(=O)(=O)[O-] -
Source
Synthetic
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Research areas
Images
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Chemical Structure - SAM e (S-(5-Adenosyl)-L-methionine disulfate tosylate), Methyl donor (ab142221)2D chemical structure image of ab142221, SAM e (S-(5-Adenosyl)-L-methionine disulfate tosylate), Methyl donor
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab142221 has been referenced in 1 publication.
- Vershinin Z et al. BRD4 methylation by the methyltransferase SETD6 regulates selective transcription to control mRNA translation. Sci Adv 7:N/A (2021). PubMed: 34039605