SB 242084 hydrochloride, 5-HT2C antagonist (ab120519)
Key features and details
- Potent, selective 5-HT2C antagonist
- CAS Number: 1260505-34-7
- Purity: > 98%
- Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
SB 242084 hydrochloride, 5-HT2C antagonist -
Description
Potent, selective 5-HT2C antagonist -
Alternative names
- SB242084
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Purity
> 98% -
CAS Number
1260505-34-7 -
Chemical structure
Properties
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Chemical name
6-Chloro-2,3-dihydro-5-methyl-N-[6-[(2-methyl-3-pyridinyl)oxy]-3-pyridinyl]-1H-indole-1-carboxamide hydrochloride -
Molecular weight
431.32 -
Molecular formula
C21H19ClN4O2.HCl -
PubChem identifier
72201049 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=CC2=C(C=C1Cl)N(CC2)C(=O)NC3=CN=C(C=C3)OC4=C(N=CC=C4)C.Cl -
Source
Synthetic
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Research areas
Images
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Chemical Structure - SB 242084 hydrochloride, 5-HT2C antagonist (ab120519)2D chemical structure image of ab120519, SB 242084 hydrochloride, 5-HT2C antagonist
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (1)
ab120519 has been referenced in 1 publication.
- Gannon BM et al. Inhibition of Cocaine and 3,4-Methylenedioxypyrovalerone (MDPV) Self-Administration by Lorcaserin Is Mediated by 5-HT2C Receptors in Rats. J Pharmacol Exp Ther 364:359-366 (2018). PubMed: 29217539