Staurosporine (DMSO solution), protein kinase inhibitor (ab146588)
Key features and details
- Protein kinase inhibitor
- CAS Number: 62996-74-1
- Purity: > 98%
- Supplied in DMSO (1mM)
- Form / State: Liquid
- Source: Synthetic
Overview
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Product name
Staurosporine (DMSO solution), protein kinase inhibitor -
Description
Protein kinase inhibitor -
Purity
> 98% -
CAS Number
62996-74-1 -
Chemical structure
Properties
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Chemical name
[9S-(9α,10β,11β,13α)]-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3,2,1-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one -
Molecular weight
466.54 -
Molecular formula
C28H26N4O3 -
PubChem identifier
44259 -
Storage instructions
Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes. -
Solubility overview
Supplied in DMSO (1mM) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C6NCc5c2c4n(c1ccccc12)[C@@]3(C)O[C@H](C[C@@H](NC)[C@H]3OC)n7c4c(c56)c8ccccc78 -
Source
Synthetic
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Research areas
Images
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Chemical Structure - Staurosporine (DMSO solution), protein kinase inhibitor (ab146588)2D chemical structure image of ab146588, Staurosporine (DMSO solution), protein kinase inhibitor
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (3)
ab146588 has been referenced in 3 publications.
- O'Callaghan P et al. Piezo1 activation attenuates thrombin-induced blebbing in breast cancer cells. J Cell Sci 135:N/A (2022). PubMed: 35274124
- Akande OE et al. DBC1 Regulates p53 Stability via Inhibition of CBP-Dependent p53 Polyubiquitination. Cell Rep 26:3323-3335.e4 (2019). PubMed: 30893604
- Lynch JM et al. Mutant myocilin impacts sarcomere ultrastructure in mouse gastrocnemius muscle. PLoS One 13:e0206801 (2018). PubMed: 30395621