Streptozocin, Pancreatic beta-cell toxin (ab142155)
Key features and details
- Selective pancreatic β-cell toxin
- CAS Number: 18883-66-4
- Purity: > 95%
- Soluble in water to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Stretomyces achromogenes
Overview
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Product name
Streptozocin, Pancreatic beta-cell toxin -
Description
Selective pancreatic β-cell toxin -
Purity
> 95% -
General notes
This product is manufactured by BioVision, an Abcam company and was previously called 1930 Streptozocin. 1930-500 is the same size as the 500 mg size of ab142155.
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CAS Number
18883-66-4 -
Chemical structure
Properties
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Chemical name
2-Deoxy-2-[[(methylnitrosoamino)carbonyl]amino-D-glucose -
Molecular weight
265.22 -
Molecular formula
C8H15N3O7 -
PubChem identifier
7067772 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN(C(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1O)CO)O)O)N=O -
Source
Stretomyces achromogenes
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Research areas
Images
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Chemical Structure - Streptozocin, Pancreatic beta-cell toxin (ab142155)2D chemical structure image of ab142155, Streptozocin, Pancreatic beta-cell toxin
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (8)
ab142155 has been referenced in 8 publications.
- Wang G et al. Exenatide exerts a neuroprotective effect against diabetic cognitive impairment in rats by inhibiting apoptosis: Role of the JNK/c-JUN signaling pathway. Mol Med Rep 25:N/A (2022). PubMed: 35119079
- Albasher G et al. Urolithin A prevents streptozotocin-induced diabetic cardiomyopathy in rats by activating SIRT1. Saudi J Biol Sci 29:1210-1220 (2022). PubMed: 35241966
- ALTamimi JZ et al. Ellagic acid improved diabetes mellitus-induced testicular damage and sperm abnormalities by activation of Nrf2. Saudi J Biol Sci 28:4300-4310 (2021). PubMed: 34354412
- Almatroodi SA et al. 6-Gingerol, a Bioactive Compound of Ginger Attenuates Renal Damage in Streptozotocin-Induced Diabetic Rats by Regulating the Oxidative Stress and Inflammation. Pharmaceutics 13:N/A (2021). PubMed: 33670981
- Altamimi JZ et al. Ellagic acid protects against diabetic cardiomyopathy in rats by stimulating cardiac silent information regulator 1 signaling. J Physiol Pharmacol 71:N/A (2020). PubMed: 33901999
- Zhang L et al. Strawberry Leaf Extract Treatment Alleviates Cognitive Impairment by Activating Nrf2/HO-1 Signaling in Rats With Streptozotocin-Induced Diabetes. Front Aging Neurosci 12:201 (2020). PubMed: 32792939
- Puelles VG et al. mTOR-mediated podocyte hypertrophy regulates glomerular integrity in mice and humans. JCI Insight 4:N/A (2019). PubMed: 31534053
- Tian Z et al. Effects of butylphthalide on cognitive decline in diabetic rats. Mol Med Rep 16:9131-9136 (2017). PubMed: 28990110