Key features and details
- DNA alkylating/methylating chemotherapeutic agent
- CAS Number: 85622-93-1
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameTemozolomide, DNA alkylating/methylating chemotherapeutic agent
DescriptionDNA alkylating/methylating chemotherapeutic agent
DNA alkylating/methylating chemotherapeutic agent. Inhibits DNA replication. Anti-cancer and apoptotic activity in vitro and in vivo. Crosses the blood-brain barrier.
Storage instructionsStore at +4°C. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141055 has been referenced in 1 publication.
- Yu J et al. SOCS5 contributes to temozolomide resistance in glioblastoma by regulating Bcl-2-mediated autophagy. Bioengineered 13:14125-14137 (2022). PubMed: 35730472