CD63 Exosome Capture Beads (ab239686)

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Key features and details

  • Detection method: Fluorescent
  • Platform: Flow cytometer
  • Sample type: Cell culture supernatant, Plasma, Urine

Overview

  • Product name

    CD63 Exosome Capture Beads
    See all Exosome kits

  • Detection method

    Fluorescent

  • Sample type

    Cell culture supernatant, Urine, Plasma

  • Species reactivity

    Reacts with: Human

  • Product overview

    CD63 Exosome Capture Beads (ab239686) consists of a simple bead population, coated with a capture antibody (CD63) for isolation/detection of exosome.


    The beads are intended for the immunoisolation (immunomagnetic or FACS) and Flow Cytometry analysis of pre-enriched CD63+ human exosomes from biofluids (plasma, urine) or cell culture media.


    These capture beads are used in the Exosome Isolation and Analysis Kits ab239684 (CD63/CD81, Urine), ab239683 (CD63/CD81, plasma), ab239682 (CD63/CD81, cell culture), ab228565 (CD63/CD9, plasma), ab228564 (CD63/CD9, cell culture).

  • Platform

    Flow cytometer

Properties

  • Storage instructions

    Store at +4°C. Please refer to protocols.
  • Components 25 tests
    CD63+ [Clone TEA3/18] capture beads 1 x 1250µl

  • Relevance

    Exosomes are best defined as extracellular vesicles that are released from cells upon fusion of an intermediate endocytic compartment, the multivesicular body (MVB), with the plasma membrane. This liberates intraluminal vesicles (ILVs) into the extracellular milieu and the vesicles thereby released are what we know as exosomes. They contain abundant proteins, DNA, mRNA, and non-coding RNAs. They are now considered as an additional mechanism for intercellular communication, allowing cells to exchange proteins, lipids and genetic material. Increasing studies have shown that exosomes play an important role in tumour initiation, growth, progression, metastasis, drug resistance and immune escape.

References (1)

Publishing research using ab239686? Please let us know so that we can cite the reference in this datasheet.

ab239686 has been referenced in 1 publication.

  • Zhou J  et al. High-throughput single-EV liquid biopsy: Rapid, simultaneous, and multiplexed detection of nucleic acids, proteins, and their combinations. Sci Adv 6:N/A (2020). PubMed: 33219024

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