Non-Homologous End Joining (H2A.X, gamma H2A.X pS139, DNA Ligase IV, Ku70, Ku80) Antibody Panel (ab213658)
Overview
-
Product name
Non-Homologous End Joining (H2A.X, gamma H2A.X pS139, DNA Ligase IV, Ku70, Ku80) Antibody Panel -
Product overview
ab213658 is a Non Homologous End Joining Panel designed for the detection and characterization of key proteins involved in DNA double strand break (DSB) repair by non-homologous end joining (NHEJ). Histone H2A.X is phosphorylated on S139, termed gamma H2A.X, at sites of DNA damage. DNA DSB repair by NHEJ requires Ku70/Ku80 heterodimer binding to the DSB, as well as DNA Ligase IV for ligation of DNA ends.
This panel contains 5 recombinant rabbit monoclonal antibodies. They are provided as a sampler panel to allow you to easily evaluate each in your applications.
The panel contains:
- Rabbit monoclonal anti-Histone H2A.X antibody [EPR895] - ChIP Grade (ab124781)
- Rabbit monoclonal anti-gamma H2A.X (phospho S139) antibody [EP854(2)Y] - ChIP Grade (ab81299)
- Rabbit monoclonal anti-DNA Ligase IV/LIG4 antibody [EPR16531] (ab193353)
- Rabbit monoclonal anti-Ku70 antibody [EPR4027] (ab92450)
- Rabbit monoclonal anti-Ku80 antibody [EPR3468] (ab80592)
For guidelines on how to use each antibody within the panel, please consult the individual datasheet for each antibody.
-
Notes
Explore our range of antibody sample panels designed to provide you with a variety of trial-size antibodies in a convenient and cost-effective format.
Properties
-
Storage instructions
Store at -20°C. Please refer to protocols. -
Components 1 units ab193353 - Anti-DNA Ligase IV/LIG4 antibody [EPR16531] 2 x 10µl ab81299 - Anti-gamma H2A.X (phospho S139) antibody [EP854(2)Y] - ChIP Grade 2 x 10µl ab124781 - Anti-Histone H2A.X antibody [EPR895] - ChIP Grade 2 x 10µl ab92450 - Anti-Ku70 antibody [EPR4027] 2 x 10µl ab80592 - Anti-Ku80 antibody [EPR3468] 2 x 10µl -
Research areas
-
Cellular localization
Ku70: Nucleus. Chromosome. Ku80: Nucleus. Chromosome. DNA Ligase IV/LIG4: Nucleus. Histone H2A.X: Nucleus. Chromosome. gamma H2A.X: Nucleus. Chromosome.
Associated products
-
Related Products
- Alexa Fluor® 488 Anti-gamma H2A.X (phospho S139) antibody [EP854(2)Y] (ab195188)
- Alexa Fluor® 647 Anti-gamma H2A.X (phospho S139) antibody [EP854(2)Y] (ab195189)
- HRP Anti-gamma H2A.X (phospho S139) antibody [EP854(2)Y] (ab195190)
- Alexa Fluor® 488 Anti-Ku80 antibody [EPR3468] (ab198586)
- Alexa Fluor® 647 Anti-Ku80 antibody [EPR3468] (ab198587)
- Alexa Fluor® 488 Anti-Ku70 antibody [EPR4027] (ab199225)
- Alexa Fluor® 555 Anti-gamma H2A.X (phospho S139) antibody [EP854(2)Y] (ab206900)
- Anti-gamma H2A.X (phospho S139) antibody [EP854(2)Y] - BSA and Azide free (ab215967)
- Anti-Histone H2A.X antibody [EPR895] - BSA and Azide free (ab217838)
- Alexa Fluor® 488 Anti-Histone H2A.X antibody [EPR895] - Nuclear Marker (ab218347)
- Alexa Fluor® 647 Anti-DNA Ligase IV/LIG4 antibody [EPR16531] (ab225387)
- Anti-Ku80 antibody [EPR3468] - BSA and Azide free (ab232381)
- Anti-DNA Ligase IV/LIG4 antibody [EPR16531] - BSA and Azide free (ab232658)
- Anti-Ku70 antibody [EPR4027] - BSA and Azide free (ab239912)
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
-
SDS download
-
Datasheet download
References (0)
ab213658 has not yet been referenced specifically in any publications.