Anti-ALDH3A1 antibody (ab103895)
Key features and details
- Goat polyclonal to ALDH3A1
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-ALDH3A1 antibody
See all ALDH3A1 primary antibodies -
Description
Goat polyclonal to ALDH3A1 -
Host species
Goat -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
Synthetic peptide:
RYPPSPAKMTQH
by a Cysteine residue linker, corresponding to C terminal amino acids 442-453 of Human ALDH3A1 (NP_000682.3) -
Positive control
- Mouse Eye Lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, Tris buffered saline -
Concentration information loading... -
Purity
Immunogen affinity purified -
Purification notes
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab103895 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P |
Use a concentration of 3 - 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
|
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| WB |
Use a concentration of 0.01 - 0.03 µg/ml. Predicted molecular weight: 50 kDa.
1 hour primary incubation is recommended for this product. |
| Notes |
|---|
|
IHC-P
Use a concentration of 3 - 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
|
WB
Use a concentration of 0.01 - 0.03 µg/ml. Predicted molecular weight: 50 kDa. 1 hour primary incubation is recommended for this product. |
Target
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Function
ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes. -
Tissue specificity
High levels in stomach, esophagus and lung; low level in the liver and kidney. -
Sequence similarities
Belongs to the aldehyde dehydrogenase family. -
Cellular localization
Cytoplasm. - Information by UniProt
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Database links
- Entrez Gene: 218 Human
- Entrez Gene: 11670 Mouse
- Omim: 100660 Human
- SwissProt: P30838 Human
- SwissProt: P47739 Mouse
- Unigene: 531682 Human
- Unigene: 4257 Mouse
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Alternative names
- Acetaldehyde dehydrogenase 3 antibody
- AHD 4 antibody
- AHD C antibody
see all
Images
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Western blot - Anti-ALDH3A1 antibody (ab103895)Anti-ALDH3A1 antibody (ab103895) at 0.01 µg/ml + Mouse Eye Lysate in RIPA buffer at 35 µg
Developed using the ECL technique.
Predicted band size: 50 kDa
Protocols
Datasheets and documents
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Datasheet download
References (1)
ab103895 has been referenced in 1 publication.
- Chu A et al. Aldehyde dehydrogenase isoforms and inflammatory cell populations are differentially expressed in term human placentas affected by intrauterine growth restriction. Placenta 81:9-17 (2019). PubMed: 31138432
