Recombinant Alexa Fluor® 488 Anti-PD-L1 antibody [CAL10] (ab310957)
![Alexa Fluor® 488 Anti-PD-L1 antibody [CAL10] (ab310957)](https://www.abcam.com/ps/products/310/ab310957/Images/ab310957-1-MTOConjugatedRecombinantAntibodyBenefits.jpg "Alexa Fluor® 488 Anti-PD-L1 antibody [CAL10] (ab310957)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Alexa Fluor® 488 Rabbit monoclonal [CAL10] to PD-L1
- Suitable for: Target binding affinity, Antibody labelling
- Conjugation: Alexa Fluor® 488. Ex: 495nm, Em: 519nm
Related conjugates and formulations
Overview
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Product name
Alexa Fluor® 488 Anti-PD-L1 antibody [CAL10]
See all PD-L1 primary antibodies -
Description
Alexa Fluor® 488 Rabbit monoclonal [CAL10] to PD-L1 -
Host species
Rabbit -
Conjugation
Alexa Fluor® 488. Ex: 495nm, Em: 519nm -
Tested applications
Suitable for: Target binding affinity, Antibody labellingmore details -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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General notes
This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling.
For suitable applications and species reactivity, please refer to the unconjugated version of this clone. This conjugated antibody is eligible for Abtrial: learn more here.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. Store In the Dark. -
Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 30% Glycerol (glycerin, glycerine), 1% BSA, 68% PBS -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
CAL10 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
- Anti-PD-L1 antibody [CAL10] - BSA and Azide free (ab251611)
- Anti-PD-L1 antibody [CAL10] – Mouse IgG1 (Chimeric) – BSA and Azide free (ab279304)
- Anti-PD-L1 antibody [CAL10] – Mouse IgG2a (Chimeric) – BSA and Azide free (ab279305)
- Anti-PD-L1 antibody [CAL10] – Rat IgG2a (Chimeric) – BSA and Azide free (ab279306)
- Alexa Fluor® 555 Anti-PD-L1 antibody [CAL10] (ab307643)
- Alexa Fluor® 594 Anti-PD-L1 antibody [CAL10] (ab311663)
- Alexa Fluor® 568 Anti-PD-L1 antibody [CAL10] (ab312937)
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab310957 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Target binding affinity |
Use at an assay dependent concentration.
|
|
| Antibody labelling |
Use at an assay dependent concentration.
|
| Notes |
|---|
|
Target binding affinity
Use at an assay dependent concentration. |
|
Antibody labelling
Use at an assay dependent concentration. |
Target
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Function
Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production. -
Tissue specificity
Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes. -
Sequence similarities
Belongs to the immunoglobulin superfamily. BTN/MOG family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Cellular localization
Cell membrane and Endomembrane system. - Information by UniProt
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Alternative names
- B7 H antibody
- B7 H1 antibody
- B7 homolog 1 antibody
see all
Images
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Alexa Fluor® 488 Anti-PD-L1 antibody [CAL10] (ab310957)
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab310957 has not yet been referenced specifically in any publications.