Recombinant Alexa Fluor® 555 Anti-Pan Trk antibody [EPR17341] (ab313243)
![Alexa Fluor® 555 Anti-Pan Trk antibody [EPR17341] (ab313243)](https://www.abcam.com/ps/products/313/ab313243/Images/ab313243-1-MTOConjugatedRecombinantAntibodyBenefits.jpg "Alexa Fluor® 555 Anti-Pan Trk antibody [EPR17341] (ab313243)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Alexa Fluor® 555 Rabbit monoclonal [EPR17341] to Pan Trk
- Suitable for: Target binding affinity, Antibody labelling
- Conjugation: Alexa Fluor® 555. Ex: 555nm, Em: 565nm
Related conjugates and formulations
Overview
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Product name
Alexa Fluor® 555 Anti-Pan Trk antibody [EPR17341]
See all Pan Trk primary antibodies -
Description
Alexa Fluor® 555 Rabbit monoclonal [EPR17341] to Pan Trk -
Host species
Rabbit -
Conjugation
Alexa Fluor® 555. Ex: 555nm, Em: 565nm -
Tested applications
Suitable for: Target binding affinity, Antibody labellingmore details -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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General notes
This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling.
For suitable applications and species reactivity, please refer to the unconjugated version of this clone. This conjugated antibody is eligible for Abtrial: learn more here.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. Store In the Dark. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 30% Glycerol (glycerin, glycerine), 1% BSA, 68% PBS -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR17341 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
- Anti-Pan Trk antibody [EPR17341] - BSA and Azide free (ab218577)
- Alexa Fluor® 488 Anti-Pan Trk antibody [EPR17341] (ab308600)
- Alexa Fluor® 647 Anti-Pan Trk antibody [EPR17341] (ab311129)
- Alexa Fluor® 594 Anti-Pan Trk antibody [EPR17341] (ab311762)
- Alexa Fluor® 568 Anti-Pan Trk antibody [EPR17341] (ab313042)
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab313243 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Target binding affinity |
Use at an assay dependent concentration.
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| Antibody labelling |
Use at an assay dependent concentration.
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| Notes |
|---|
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Target binding affinity
Use at an assay dependent concentration. |
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Antibody labelling
Use at an assay dependent concentration. |
Target
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Relevance
Family of neurotrophic tyrosine kinase (NTRK1/2/3) genes which encode TrkA, TrkB and TrkC protein kinases. The three family members are activated by different neurotrophins: TrkA is activated by Nerve growth factor (NGF), TrkB by Brain-derived neurotrophic factor (BDNF) or neurotrophin-4 (NT-4) and TrkC by NT-3. Neurotrophin signalling activates cellular pathways involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. Localization TrkA: Cell membrane. Early endosome membrane. Late endosome membrane. Internalized to endosomes upon binding of NGF or NT-3 and further transported to the cell body via a retrograde axonal transport. Localized at cell membrane and early endosomes before nerve growth factor (NGF) stimulation. Recruited to late endosomes after NGF stimulation. Colocalized with RAPGEF2 at late endosomes (By similarity). TrkB: Membrane. TrkC: Membrane. -
Alternative names
- BDNF/NT-3 growth factors receptor antibody
- EML4 antibody
- ETV6 antibody
see all
Images
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Alexa Fluor® 555 Anti-Pan Trk antibody [EPR17341] (ab313243)
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab313243 has not yet been referenced specifically in any publications.