Anti-Arp3 antibody [FMS338] (ab49671)
Key features and details
- Mouse monoclonal [FMS338] to Arp3
- Suitable for: ICC/IF, WB, Indirect ELISA
- Reacts with: Mouse, Rat, Dog, Human, African green monkey
- Isotype: IgG2b
Overview
-
Product name
Anti-Arp3 antibody [FMS338]
See all Arp3 primary antibodies -
Description
Mouse monoclonal [FMS338] to Arp3 -
Host species
Mouse -
Tested applications
Suitable for: ICC/IF, WB, Indirect ELISAmore details -
Species reactivity
Reacts with: Mouse, Rat, Dog, Human, African green monkey -
Immunogen
Recombinant full length protein (Human)
-
Positive control
- Whole cell lysate of mouse myoblast C2 cells.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 7.40
Preservative: 0.097% Sodium azide
Constituent: 0.0268% PBS -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Clonality
Monoclonal -
Clone number
FMS338 -
Myeloma
NS1 -
Isotype
IgG2b -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab49671 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
ICC/IF | (1) |
Use a concentration of 10 µg/ml.
|
WB | (1) |
Use at an assay dependent concentration.
|
Indirect ELISA |
Use at an assay dependent concentration.
Array: Use at an assay dependent dilution. |
Notes |
---|
ICC/IF
Use a concentration of 10 µg/ml. |
WB
Use at an assay dependent concentration. |
Indirect ELISA
Use at an assay dependent concentration. Array: Use at an assay dependent dilution. |
Target
-
Relevance
The Arp2/3 complex involved in Golgi polerization in NIH3T3 cells. In a different model it has been shown that the Arp2/3 complex is necessary for neutrophil chemotaxis and phagocytosis. -
Cellular localization
Cytoplasmic -
Database links
- Entrez Gene: 403702 Dog
- Entrez Gene: 10096 Human
- Omim: 604222 Human
- SwissProt: P61158 Human
-
Alternative names
- Actin like protein 3 antibody
- Actin related protein 3 antibody
- ACTR3 antibody
- ARP3 actin related protein 3 homolog (yeast) antibody
Images
Protocols
Datasheets and documents
-
SDS download
-
Datasheet download
References (27)
ab49671 has been referenced in 27 publications.
- Aggarwal A et al. Embedding of HIV Egress within Cortical F-Actin. Pathogens 11:N/A (2022). PubMed: 35056004
- Bera K et al. Extracellular fluid viscosity enhances cell migration and cancer dissemination. Nature 611:365-373 (2022). PubMed: 36323783
- Ji Y et al. Poststroke dendritic arbor regrowth requires the actin nucleator Cobl. PLoS Biol 19:e3001399 (2021). PubMed: 34898601
- Pinzaru AM et al. Replication stress conferred by POT1 dysfunction promotes telomere relocalization to the nuclear pore. Genes Dev 34:1619-1636 (2020). PubMed: 33122293
- Lachowski D et al. G Protein-Coupled Estrogen Receptor Regulates Actin Cytoskeleton Dynamics to Impair Cell Polarization. Front Cell Dev Biol 8:592628 (2020). PubMed: 33195261