Anti-CA19-9 antibody [121SLE] (ab3982)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CA19-9 antibody [121SLE] (ab3982)](https://www.abcam.com/ps/products/3/ab3982/Images/ab3982-8456-anti-ca19-9-antibody-121sle-immunohistochemistry.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CA19-9 antibody [121SLE] (ab3982)")
Key features and details
- Mouse monoclonal [121SLE] to CA19-9
- Suitable for: IHC-P, ELISA, Flow Cyt
- Reacts with: Human
- Isotype: IgM
Overview
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Product name
Anti-CA19-9 antibody [121SLE]
See all CA19-9 primary antibodies -
Description
Mouse monoclonal [121SLE] to CA19-9 -
Host species
Mouse -
Specificity
The antibody recognizes Sialyl Lewis a containing glycolipids. -
Tested applications
Suitable for: IHC-P, ELISA, Flow Cytmore details -
Species reactivity
Reacts with: Human -
Immunogen
Tissue, cells or virus corresponding to CA19-9. Immunoprecipitate obtained after immunodiffusion of MAb 19-9 and mucins isolated from an ovarian cyst of a 0Le(a+b-) patient.
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Positive control
- IHC-P: Colorectal adenocarcinoma.
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General notes
This product was changed from ascites to tissue culture supernatant. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. Do Not Freeze. -
Storage buffer
pH: 8.0
Preservative: 0.097% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity
Proprietary Purification -
Purification notes
Purified from TCS. Purified by precipitation and chromatography. Purity >95% by SDS-PAGE. -
Clonality
Monoclonal -
Clone number
121SLE -
Isotype
IgM -
Research areas
Associated products
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Compatible Secondaries
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Conjugation kits
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab3982 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P |
1/100.
|
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| ELISA |
Use at an assay dependent concentration.
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| Flow Cyt |
Use at an assay dependent concentration. PubMed: 22490524
ab91545 - Mouse monoclonal IgM, is suitable for use as an isotype control with this antibody. |
| Notes |
|---|
|
IHC-P
1/100. |
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ELISA
Use at an assay dependent concentration. |
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Flow Cyt
Use at an assay dependent concentration. PubMed: 22490524 ab91545 - Mouse monoclonal IgM, is suitable for use as an isotype control with this antibody. |
Target
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Alternative names
- CA19.9 antibody
- Ovarian tumor antigen antibody
- Pancreatic tumor antigen antibody
- Sialyl Lewis a antibody
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CA19-9 antibody [121SLE] (ab3982)
ab3982 staining CA19-9 in human colorectal adenocarcinoma by IHC-P (Formalin/Paraformaldehye fixed paraffin embedded tissue sections).
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (16)
ab3982 has been referenced in 16 publications.
- Purohit S & She JX Multiplex Glycan Bead Array (MGBA ) for High Throughput and High Content Analyses of Glycan-Binding Proteins Including Natural Anti-Glycan Antibodies. Methods Mol Biol 2460:33-44 (2022). PubMed: 34972929
- Miró L et al. Sialyltransferase Inhibitor Ac53FaxNeu5Ac Reverts the Malignant Phenotype of Pancreatic Cancer Cells, and Reduces Tumor Volume and Favors T-Cell Infiltrates in Mice. Cancers (Basel) 14:N/A (2022). PubMed: 36551619
- Liu X et al. RNA-binding protein with serine-rich domain 1 regulates microsatellite instability of uterine corpus endometrial adenocarcinoma. Clinics (Sao Paulo) 76:e3318 (2021). PubMed: 34817046
- Starzonek S et al. Systematic analysis of the human tumor cell binding to human vs. murine E- and P-selectin under static vs. dynamic conditions. Glycobiology 30:695-709 (2020). PubMed: 32103235
- Hu H et al. MicoRNA-301a Promotes Pancreatic cancer Invasion and Metastasis through the JAK/STAT3 Signaling Pathway by Targeting SOCS5. Carcinogenesis N/A:N/A (2019). PubMed: 31233116