Anti-CCK1-R antibody (ab75153)
Key features and details
- Rabbit polyclonal to CCK1-R
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-CCK1-R antibody
See all CCK1-R primary antibodies -
Description
Rabbit polyclonal to CCK1-R -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat
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Immunogen
Synthetic peptide corresponding to Human CCK1-R (internal sequence).
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Positive control
- Extracts from HUVEC cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS
Without Mg2+ and Ca2+ -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab75153 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB |
1/500 - 1/1000. Predicted molecular weight: 48 kDa.
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| Notes |
|---|
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WB
1/500 - 1/1000. Predicted molecular weight: 48 kDa. |
Target
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Function
Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 886 Human
- Entrez Gene: 12425 Mouse
- Entrez Gene: 24889 Rat
- Omim: 118444 Human
- SwissProt: P32238 Human
- SwissProt: O08786 Mouse
- SwissProt: P30551 Rat
- Unigene: 129 Human
see all -
Alternative names
- CCK A antibody
- CCK A receptor antibody
- CCK AR antibody
see all
Images
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Western blot - Anti-CCK1-R antibody (ab75153)All lanes : Anti-CCK1-R antibody (ab75153) at 1/500 dilution
Lane 1 : Extracts from HUVEC cells
Lane 2 : Extracts from HUVEC cells with immunising peptide at 5 µg
Lysates/proteins at 5 µg per lane.
Predicted band size: 48 kDa
Observed band size: 45 kDa why is the actual band size different from the predicted?
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab75153 has been referenced in 3 publications.
- Huang L et al. Changes in the interstitial cells of Cajal in the gallbladder of guinea pigs fed a lithogenic diet. Exp Ther Med 22:823 (2021). PubMed: 34131446
- Guo L et al. Inhibitory effect of high leucine concentration on a-amylase secretion by pancreatic acinar cells: possible key factor of proteasome. Biosci Rep 38:N/A (2018). PubMed: 30361293
- Duraisamy AJ et al. Changes in ghrelin, CCK, GLP-1, and peroxisome proliferator-activated receptors in a hypoxia-induced anorexia rat model. Endokrynol Pol 66:334-41 (2015). PubMed: 26323471